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Biochem Biophys Res Commun 354:259264 Larghero P, Vene R, Minghelli S, Travaini G, Morini M, Ferrari N, Pfeffer U, Noonan DM, Albini A, Benelli R (2007) Biological assays and genomic analysis reveal lipoic acid modulation of endothelial cell behavior and gene expression

39,40 This observation suggests the presence of a significant residual cardiovascular risk, that is, the component of an individual patients cardiovascular risk that is not influenced by existing treatments