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First, this approach assesses the patients condition through quantitative clinical and biomarker scores rather than merely considering the presence or absence of MDD as a binary variable (thus, only one bit of information)

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doi: 10.1038/nrendo.2016.116 33 KoopmanLAKopcowHDRybalovBBoysonJEOrangeJSSchatzFet al

Histones are made of two domains differing in both structure and function

By optimising the dosing schedule to align with the rhythmic changes in drug absorption, metabolism, and target organ sensitivity, we may be able to improve therapeutic outcomes

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