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Thiamine and thiamine diphosphate (TDP) concentrations are reduced by 20% in cancer patients blood, transketolase activity is reduced by 20%, and the TDP impact is reduced by 542% (86) ( Table 2 )

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R SULT2A1 polymorphisms affect DHEA sulfation and may influence adrenal hormone metabolism

It also activates the Wnt/beta-catenin signaling pathway, which is critical for follicle development and cycling

Rodriguez-Colman MJ, Dansen TB, Burgering BMT (2024) FOXO transcription factors as mediators of stress adaptation

doi: 10.3389/fnut.2025.1585922 Received 01 March 2025 Accepted 28 April 2025 Published 16 May 2025 Volume 12 - 2025 Edited by Mark Elisabeth Willems, University of Chichester, United Kingdom Reviewed by Luiz Royes, Federal University of Santa Maria, Brazil Alessandra DAmico, Sapienza University of Rome, Italy Lillian Morton, The University of Auckland, New Zealand Updates Copyright 2025 Wang and Yu