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The results of another randomized trial in 39 patients with Alzheimers disease suggested that supplementation with fish oil concentrate (high in omega-3 fatty acids) with or without lipoic acid (600 mg/day) for one year could delay the progression in cognitive and functional impairments assessed by the Instrumental Activities of Daily Living (IADL) scoring system compared to placebo (104)

In contrast, the nanoparticles NP4 had a much longer blood circulation half-life time of 2.97 h (Supplementary Fig

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Group one received a placebo