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Isotope-labelled PGRMC1 proteins for NMR analyses were prepared by growing cells (BL21 (DE3)) in minimal M9 media in H 2 O or 99.9% 2 H 2 O, including ampicillin, metals, vitamins, 15 N-ammonium chloride and 13 C or 12 C glucose as sources of nitrogen and carbon, respectively

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Osteoporosis is characterized by deterioration of bone tissue and is a major concern in Western countries

In the present study, AB4 improved lung pathological changes, reduced the levels of MDA, DHE and PTGS2, while increasing the expression of GSH, GPX4, and SLC7A11