interaction of chloroacetamide electrophiles with cellular glutathion Glutathione dynamics in subcellular compartments and implications for drug development Selective covalent targeting of GPX4
Selective covalent targeting of GPX4 using masked nitrile oxide electrophiles Nature Chemical Biology Covalent inhibitors of bacterial peptidoglycan biosynthesis enzyme MurA with chloroacetamide warhead ScienceDirect Exploring the synergetic role of cuproptosis and ferroptosis and their implication in advancing cancer therapeutics Discover Oncology Springer Nature Link Delineating cysteine reactive compound modulation of cellular proteostasis processes Nature Chemical Biology Heat Shock Protein 90 Interactome Mediated Proteolysis Targeting Chimera (HIM PROTAC) Degrading Glutathione Peroxidase 4 to Trigger Ferroptosis Journal of Medicinal Chemistry Targeting a Therapy Resistant Cancer Cell State Using Masked Electrophiles as GPX4 Inhibitors bioRxiv
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