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Principal component analysis showed that the cluster of all three repeats in the M group almost completely separates from the CTR group, the cluster of VM group has the largest overlap with CTR group, and the cluster of PM group has some overlap with both M and CTR groups (Supplementary Fig

It was noted that during the incubation with experimental media (4060 mg/L), yeast cells took a long time to adapt to the new environment, and the duration of the adaptation phase was much longer than that in the control medium or in those supplemented with lower doses of selenium

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The tumor-bearing mice pretreated with vitamin E lived longer on average than those treated with doxorubicin alone