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Parkinson's disease: from pathogenesis to pharmacogenomics

The fixed effect of milk intake is illustrated in Figure 5

90 In the cardiovascular system, ketones serve as an energy source for cardiac muscle and endothelial cells

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By decoupling mitochondrial electron transport chain (mtETC) activity from ATP production, UNCOUPLING PROTEIN 1 (UCP1) limits excessive reactive oxygen species (ROS) formation, thereby preventing over-reduction of mtETC proteins (Nakano et al., 2006)