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A 2021 peer-reviewed review of NNMT in obesity and type 2 diabetes states explicitly that 'clinical trials targeting NNMT have not been reported' meaning every quantitative efficacy figure available for this compound comes from mice, and there is currently zero published human efficacy data

Some GPs may incorrectly believe that only patients with a definite diagnosis of PA, those with a positive intrinsic factor antibody test, require treatment for life so seem to be using this as their treatment exclusion criteria

The chart above shows this accumulation pattern, with the sawtooth pattern representing the rise after each dose and decay between doses

The Power Of An At-Home B12 Test The most direct way to get this clarity is with an at-home Vitamin B12 test

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