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hydrophila was treated with escalating PMP concentrations (0, 0.1, 1, and 10 mg/mL, designated as Control, PMP1, PMP2 and PMP3), and D-cycloserine (0.5 mg/mL, positive control) (Fig

While eNOS activation at optimal levels of BH 4 leads to production of NO, activation of NOS in the absence of or in the presence of decreased levels of BH 4 results in generation of superoxide rather than NO in the vascular endothelium

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3 If the product of a Phase I reaction is not soluble enough to be excreted, a Phase II conjugation reaction will typically accomplish this