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Metformin can disrupt this absorption process in several ways

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At 1 year, the adverse reactions reported to be drug-related were impotence (erectile dysfunction), decreased libido, decreased ejaculate volume, ejaculation dysfunction, breast enlargement, breast tenderness (mastalgia), and rash (unspecified)

These bacteria ferment carbohydrates, produce gas, disrupt digestion, and interfere with nutrient absorption

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