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Because this complex typically retains hydrophilic residues, it exhibits poor membrane permeability, limiting its cytotoxicity primarily to tumor cells that highly express the target antigen

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CG14500 : one-way ANOVA = 0.002, Tukeys HSD = 0.002

This occurs because heat increases the kinetic energy and causes the molecules to vibrate so rapidly and violently that the bonds are disrupted

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