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Studies of metal binding reactions in Metallothioneins by spectroscopic, molecular biology, and molecular modelling techniques

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For these reasons, an alternative assay especially for metal biologists would be a useful option to advance our understanding of metal-ligand interactions at conditions that are prevalent in the cytosol

Couturier, J., Stroher, E., Albetel, A.N., Roret, T., Muthuramalingam, M., Tarrago, L., Seidel, T., Tsan, P., Jacquot, J.P., Johnson, M.K., et al

Recent evidence has shown that at moderate concentrations, nitric oxide (NO), superoxide anion and related reactive species play an important role as regulatory mediators in cell-signalling processes and that many of the ROS-mediated responses actually protect the cells against oxidative stress and re-establish redox balance [4]