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With the admission of vitamin E, paraoxonase 1 protein has expanded in the blood, showing a decline in OS and protecting the lipids from oxidation (67)

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Recent studies demonstrate promising synergistic effects when combining EGCG with established treatments for neurodegenerative disorders

In aerobic organisms, the main reactive species are ROS (Halliwell and Gutteridge, 2015), but additional families include reactive nitrogen species (RNS) and reactive sulphur species (RSS), which interact with or enhance ROS generation (Figure 2)

Similarly, baicalein significantly improved the abnormal behaviors in MPTP-induced mice model of PD, as manifested by shortening the total time for climbing down the pole, prolonging the latent periods of rotarod, and increasing the vertical movements

Research shows that intracerebroventricular injection of soluble A-42 in wildtype rats and mice induces depressive-like behavior, as shown by increased immobility in FST (Ledo et al., 2013)