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Timing: Split into two doses per day, ideally taken with carbohydrate-containing meals to enhance absorption and uptake into muscle cells

In: Campbell M, Walsh P (eds)

In addition, in further clinical research, it was found that taking berberine orally can reduce plaque score and TMAO content in feces and plasma, showing its efficacy in regulating TMAO to prevent and treat AS (Ma et al., 2022)

Conversely, autophagy regulates both ciliogenesis and the length of the cilium through the degradation of specific proteins involved in the formation of cilia 15,16,17,18

Trimethylamine n-oxide promotes vascular inflammation through signaling of mitogen-activated protein kinase and nuclear factor-B