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10.1093/jmcb/mjab051 59 HuangF.NilholmC.RothB.LinningeC.HglundP.NymanM.et al (2018)

Neurotoxicology 92 , 131155

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5.1.3 Modulating immune and inflammatory pathways Targeting key regulators such as NF-KB and Nrf2 can not only reduce proinflammatory cytokine production but also indirectly rebalance iron homeostasis

Biochem Biophys Res Commun 438:721727 Li F, Rajendran P, Sethi G (2010) Thymoquinone inhibits proliferation, induces apoptosis and chemosensitizes human multiple myeloma cells through suppression of signal transducer and activator of transcription 3 activation pathway

To accomplish this we use green fluorescent protein (GFP)-based redox sensors we developed to measure the glutathione redox state in different subcellular compartments