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Furthermore, transglutaminase 2 can lead to neuronal death during stroke by inducing GSH depletion, thereby promoting ROS accumulation and ferroptosis (65)

J Clin Neurosci 18(11):14441448

Int J Mol Sci 22(24):13475 Ji J, Jin W, Liu SJ, Jiao Z, Li X (2023) Probiotics, prebiotics, and postbiotics in health and disease

1 REIMAGINE 2 was a 68-week phase 3 trial evaluating the safety and efficacy of CagriSema in doses 2.4 mg/2.4 mg and 1 mg/1 mg once weekly versus semaglutide 2.4 mg, semaglutide 1 mg, cagrilintide 2.4 mg, and dose-matched placebo in 2,713 adults with T2D inadequately controlled with metformin with or without an SGLT2 inhibitor