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But, those on blood thinners should be careful about how B12 could affect their treatment

Although folic acid absorption by the intestine is catalyzed by the proton-coupled folate transporter (PCFT), which has similar affinity for both folic acid and reduced folates ( Table 2 ) (65, 66), the affinity for folic acid of the reduced folate carrier (RFC), which is ubiquitously expressed in all tissues, is 50- to 150-fold lower than that for 5-methylTHF and other reduced folates (Table 2) (65, 66)

Raetz J, Wilson M, Collins K

Some patients find that taking their supplement with the largest meal of the day provides optimal tolerance

Increased serum creatinine was reported in patients with 1) underlying renal disease, 2) dehydration secondary to fever, sepsis, gastrointestinal losses, or diuretic therapy, or 3) other risk factors, such as advanced age, or concomitant nephrotoxic drugs in the post-infusion period

As per his obituary, he was a staunch Democrat as the male members of his family have ever been. As per his obituary in the Brooklyn Union , he was a man of considerable wealth who died at 230 Clinton Street in Brooklyn, where he lived with his mother