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Neither figure is a validated human dose, and both are well below the doses used in published trials

Biomarker-driven stratification tools, including the omega-3 index, serum magnesium levels, circulating selenoprotein P, and 25-hydroxyvitamin D, are emerging as critical determinants of therapeutic efficacy

However, unlike the excluded volume effect of crowding agents, the confinement effect of vesicles can be studied separately from the chemical interactions by experimental comparison with non-encapsulated RNA that is exposed to vesicles (RNA outside vesicles)

144 WuZ.PuigserverP.AnderssonU.ZhangC.AdelmantG.MoothaV.et al (1999)

Other suitable suspending agents include primary amines having a fatty alkyl moiety having at least about 16 carbon atoms, examples of which include palmitamine or stearamine, and secondary amines having two fatty alkyl moieties each having at least about 12 carbon atoms, examples of which include dipalmitoylamine or di(hydrogenated tallow)amine

5.2 Patient heterogeneity Surgical patients vary widely in age, comorbidities (diabetes, heart failure), and baseline immune status