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After 28 days, degradation may compromise research accuracy even if the solution appears unchanged

A review of the cognitive and behavioral symptoms in dementia with Lewy bodies

3.2 Regulatory mechanisms of glycolysis and oxidative phosphorylation in astrocytes Astrocytes exhibit a greater glycolytic capacity relative to oxidative phosphorylation, supported by elevated Pfkfb3-driven fructose-2,6-bisphosphate production that accelerates glycolysis, while reduced pyruvate dehydrogenase expression restricts oxidative phosphorylation (Khler et al., 2020)

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doi: 10.1007/s00394-021-02588-y 280 SuXZhangJWangHXuJHeJLiuLet al

Lysosomotropic compounds have been shown to decrease lysosomal enzyme activity as well