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Huge gastrocutaneous fistula leaking at 1st postoperative day in control rats ( c ) and dried fistula without any leakage in BPC 157 rats ( b (Skorjanec et al., 2009)

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Why GI side effects happen The area postrema sits outside the blood-brain barrier

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2: Yuan C, Demers A, Silva-Ortiz V, Hasoon JJ, Lee W, Dave K, Amirdelfan K, Burke HW, Christo PJ, Robinson CL

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As of this writing, the FDA has not yet formally published the updated Category 2 list following Secretary Kennedy's February 27, 2026 announcement

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AOD-9604 AOD-9604 is a modified fragment of human growth hormone (hGH), originally studied by pharmaceutical company Metabolic Pharmaceuticals as a potential anti-obesity compound

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Novo Nordisk filed an NDA for the CagriSema combination in December 2025, with an FDA decision anticipated in late 2026

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