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The Framingham Heart Study and the Baltimore Longitudinal Study on Aging (BLSA) showed that in healthy individuals without concomitant cardiovascular diseases, aging results in an increase in the prevalence of left ventricular hypertrophy (LVH) and fibrosis, a decline in the diastolic function, and an increase in the prevalence of cardiac arrhythmias (Lakatta and Levy, 2003b)

Association between HIV infection and mitochondrial DNA copy number in peripheral blood: A population-based, prospective cohort study

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While no difference in pCR rate was seen in the high 1 group, 64% of patients with high 2 disease achieved a pCR with immunotherapy, compared to 22%s in the paclitaxel control group [76]

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