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IGF-1 in cartilage metabolism IGF-1 promotes cartilage anabolism Proteoglycan is an essential component of the ECM

Berberine, an isoquinoline alkaloid from Coptis chinensis , disrupts Candida albicans cell-wall architecture by increasing surface exposure of -glucans and chitin, thereby weakening the barrier and heightening susceptibility to immune attack and antifungal agents (Shi et al., 2017

The exact reasons and mechanisms regarding the failure of these studies to produce the expected beneficial effects remain largely unknown

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1 Moreover, higher levels of renal nitrotyrosine, malondialdehyde (MDA), gp91 phox , p22 phox in 24-week-old SHR imply a potential involvement of oxidative stress in the maintenance of hypertension

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