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Acknowledgements We acknowledge the following team members, collaborators and other staff who have contributed to this study

Dosing & Reconstitution Guide Educational guide for reconstitution and daily dosing Standard / Gradual Approach (3 mL = ~3.33 mg/mL total) Route: Subcutaneous (SC) | Frequency: Once daily Note: The 1:1 blend ratio means tesamorelin and ipamorelin are present in equal amounts per mL

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MCH-R1 antagonists: what is keeping most research programs away from the clinic

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