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doi:10.1177/1060028015620800

According to the online magazine Vice, an opioid works on the systems that control both sleep and breathing: At the base of your brain lies a respiratory control center that drives your breathing, reacting to the level of carbon dioxide and oxygen in your blood to spur you to breathe

Examples include proton pump inhibitors (PPIs) and Histamine H2 receptor agonists (H2 blockers), which doctors prescribe to treat indigestion, heartburn, and gastroesophageal reflux disease (GERD)

Foods to avoid High-fat foods, particularly fried foods and fatty animal products, significantly worsen GI side effects on tirzepatide

The trials that support it were conducted in a population with a specific metabolic condition, and generalizing those results to general obesity is not straightforward