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Huijbers IJ, Bin Ali R, Pritchard C et al (2014) Rapid target gene validation in complex cancer mouse models using re-derived embryonic stem cells

Dig Liver Dis 2024;56:13121318.ArticlePubMed 22

However, it is not possible to selectively inhibit DYRK1A expression

The threshold Glide XP score and MMGBSA binding affinity values were set at -8 and -60 Kcal/mol respectively (based on docking scores with the substrate, glutathione) for the final screening of compounds