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These results show that, compared to the Sham + DMSO group, the CCI group exhibited a significant increase in mechanical withdrawal frequency and a decrease in thermal withdrawal latency on day 7 post-CCI, which indicates the emergence of mechanical and thermal pain hypersensitivity

These figures describe how the compound is used in research

Edaravone (3-methyl-1-phenyl-2-pyrazolin-5-one) is a free radical scavenger approved for the treatment of patients with ALS 6 , the beneficial effect of which has been suggested to be due to its ability to suppress ferroptosis 29, 30

NEDD4 lactylation promotes APAP induced liver injury through Caspase11 dependent non-canonical pyroptosis

If VitaminB12 treatment is considered suitable, it is administered by a trained practitioner in a clinical setting using sterile, single-use equipment