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Dendrimers are prospective platforms for further research in nano-immunotherapy, but they may exert non-specific toxicities which can be mitigated by structural changes and they are also insufficient for encapsulation of hydrophilic agents owing to their low hydro-solubility [106]

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The delivery method can also influence how these benefits are experienced, with injectable forms often providing stronger and more consistent outcomes, while nasal sprays may offer a more accessible entry point