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It is written strictly for research-context decision support: nothing here is a recommendation for human use, and all dose figures cited are reproduced from published animal and in vitro work for protocol-design reference only

Sowell ER, Thompson PM, Leonard CM, Welcome SE, Kan E, Toga AW (2004)

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Sometimes drugs that are poorly compounded may include too much of the active ingredients

The knockout of JAM-A, one of the key structural components of tight junctions, causes mild colitis in mice, and these mice show the increased susceptibility to DSS induced IBD (Laukoetter et al., 2007, Serek and Oleksy-Wawrzyniak, 2021)