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Ascorbic acid was shown to cause Dev R regulation by an extra process

The two supernatants were combined, the pH was adjusted to 5 with potassium hydroxide, a 10 L aliquot was collected for LC-MS analysis and the sample was frozen-dried

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After incubation, 1 ml of 4 mM methimazole (MMI) was added and cells were washed with ice-cold PBS

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After adjusting for age, sex, comorbidities, and ulcerative colitis treatment, statins showed a dose-dependent chemopreventive effect for all malignancies (P=0.002), while metformin and aspirin did not show any