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The majority of cell surface receptors are glycosylated/sialylated, and hyposialylation of muscle glycoproteins is thought to be responsible for muscle deterioration in mouse models of GNE myopathy 17,18,19,20

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At week 16, patients who did not meet the American College of Rheumatology criteria for 20% improvement (ACR20) were switched from 15mg of oral MTX to 15mg of SC MTX and from 15mg of SC MTX to 20mg of SC MTX for the remaining 8 weeks, still in a blinded manner

When amygdalin is injected intravenously at a dose of 5 mg/kg, it reaches its T max within 2 min, while oral administration takes 14 min

Genetic diversity of the plasmodium vivax multidrug resistance 1 gene in Thai parasite populations

Total protein and RNA were collected for further analysis