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Ex vivo experiments using precision-cut lung slices from IPF patients and mouse models further confirmed saracatinibs ability to downregulate fibrotic genes, reduce collagen accumulation, and decrease -SMA-positive areas

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26 A recent study by Christofides and Desai discussed the importance of monitoring albuminuria in patients with type 2 diabetes as an essential tool in the detection of onset of CKD and monitoring disease progression

Women of reproductive age are at particular risk