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Because of the inherent risk of infections and sepsis, however, splenectomy generally is reserved for use in patients older than five years with moderate to severe disease, characterized by hemoglobin concentrations of less than 11 g per dL (110 g per L) and jaundice

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In vivo detection of gamma-glutamyl-transferase up-regulation in glioma using hyperpolarized gamma-glutamyl-[1-(13)C] glycine

Disclosures: Himsikhar Khataniar: Nothing to Disclose, Aakash Desai: Nothing to Disclose, Muhammad Ali Butt: Nothing to Disclose, Michael Babich: Abbvie: Speaking and Teaching, Gilead pharma: Speaking and Teaching, Salix pharma: Speaking and Teaching, Intercept pharma: Speaking and Teaching, Madrigal pharma: Speaking and Teaching, Nabeeha Mohy-ud-din: Nothing to Disclose 1593 HEPATOCYTE-SPECIFIC DELETION OF BETAINE HOMOCYSTEINE METHYLTRANSFERASE PROMOTES ALCOHOL-INDUCED LIVER INJURY Ramachandran Rajamanickam 1 Sathish kumar Perumal 1 Poonam Sagar 1 Natalia Osna 1 Karuna Rasineni 1 Kusum Kharbanda 2 , 1 University of Nebraska Medical Center, 2 Department of Veterans Affairs, Veterans Affairs Nebraska-Western Iowa Health Care System Background: Alcohol- associated liver disease (ALD) remains a significant health concern globally

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