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Psychiatry 27 CervenkaI.AgudeloL

In a model of sepsis-induced AKI, inhibition of EZH2 expression could reduce the apoptotic and inflammatory responses of renal TEC, alleviating AKI by mitigating the transcriptional inhibition of SOX9 [34]

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Beyond these findings regarding Glu and GABA, cumulative evidence has indicated dysfunction of the Gln-Glu cycle and the excitatory versus inhibitory balance (E/I balance)