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In contrast, knockdown of RRM2 significantly inhibited the migration and invasion ability of THCA cells compared with the control group ( Figure 7C , Supplementary Figure S6 )

Suppression of copper transporter ATP7B has been linked to alterations in intracellular copper trafficking as well as lipid metabolism and cell cycle machinery in an Atp7b-/- mouse model [5, 6]

However, individuals with pre-existing medical conditions should seek medical advice first

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