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Natural polyphenols in drug delivery systems: current status and future challenges

First, -glutamylcysteine ligase (GCL) catalyzes the synthesis of -glutamylcysteine (-EC) from glutamate (Glu) and cysteine (Cys)

From an operational standpoint, Pravada also highlights its compliance with GMP standards and regulatory frameworks in both the United States and Canada

These findings remain preliminary and are based on preclinical or in-vitro research systems

hence, targeting glutamine metabolism may show therapeutic effects in these cancers

Besides its role in cancer, amino acid metabolism has been reported as an important participant in the development of metabolic diseases such as diabetes and obesity, as well as cardiovascular diseases, autoimmune diseases and neurological diseases