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Bioinformatic analysis identified IGF1R as a putative target for miR-939, which was further confirmed via luciferase assay in cell lines and supported by the observation of an inverse correlation between miR-939 and IGF1R levels in osteosarcoma tissues

120 Subsequently, the preproinsulin is translated at the cytosolic surface of the ER and then translocated into it

[PubMed: 23293189] (Commentary on the WHO global introspection method because of its specificity for liver injury and attention to alternative explanations, such as hepatitis and other viral infections)

The Fe-S cluster is an iron mitochondrial chaperone, expressed in pancreas cells and stimulated by hyperglycaemic disease [42]

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Methods: We performed a retrospective analysis based on data presented at the multidisciplinary team meetings of our tertiary care center between July 2015 and August 2021