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The hyperactivation of the gap junction protein connexin 43 (Cx43) increases the expression of p53, p16INK4a, and NF-B, which are positively correlated with aging

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Larsson SC, Woolf B, Gill D (2023) Appraisal of the causal effect of plasma caffeine on adiposity, type 2 diabetes, and cardiovascular disease: two sample mendelian randomisation study