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The search strategy employed Medical Subject Headings (MeSH) in combination with additional keywords such as Traditional Chinese Medicine, TCM, TCM herbs, diabetes mellitus, diabetic complication, diabetic retinopathy, diabetic neuropathy, diabetic nephropathy, and diabetic cardiomyopathy. These MeSH terms were integrated using Boolean operators to identify publications relevant to the research objectives

The treatment improved synaptic transmission and reduced phosphorylated Tau

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doi: 10.3389/fmolb.2016.00027 Received 15 April 2016 Accepted 07 June 2016 Published 27 June 2016 Volume 3 - 2016 Edited by Thomas Ngele, University of Vienna, Austria Reviewed by Andrea Fuso, Sapienza University of Rome, Italy

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This manifests as cramping, bloating, or vague upper abdominal fullness