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Biologic safety in psoriasis: review of long-term safety data

Quantitative Analysis To quantitatively evaluate the 1 H NMR spectra of the serum of participants at T0 in comparison to the NMR spectra of the serum of the same participants at T1, the PRincipal COmponent Normalization Algorithm (PRICONA) and normalization strategy were applied

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The present study provides a novel pathway to produce polysulfide species Cys-SSH, GSSH and persulfurated proteins as well as H 2 S 2 and H 2 S 3 , and helps clarify the cellular signaling in which these persulfurated species are involved