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Such individuals have limited NADPH reserves and a low ability to reduce the oxidised active drug metabolite (Fig

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reported that GTPSCS can translocate to the nucleus and interact with p300 to promote histone lactylation, a process that depends on the acetylation of the G2 subunit of GTPSCS [95]

Mutagenicity represents an established surrogate parameter for prediction of the carcinogenic potential, and bacteria-based mutagenicity testing has demonstrated a reasonably good correlation with carcinogenicity, especially for NAs (Bercu et al

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Diets rich in omega-3 fatty acids, antioxidants, and polyphenolssuch as fatty fish, berries, dark leafy greens, walnuts, and olive oilmay support neuronal health and reduce oxidative stress within the brain