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Bypasses Regulation: Its design limits its affinity for IGF-binding proteins (IGFBPs), which normally restrict IGF-1's activity

The GST enzymes help neutralize them by attaching glutathione, allowing them to be cleared from the body

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20 mM HEPES, 5 mM D-glucose, 145 mM NaCl, 5.4 mM KCl, 1.8 mM CaCl 2 , 1 mM MgCl 2 , 0.8 mM Na 2 HPO 4 , pH adjusted with NaOH at 37 C to 7.4) and afterwards incubated at 37 C with 200 L (all experiments without MCB) or 500 L (all experiments containing MCB) IB containing 100 M of the -glutamyltranspeptidase inhibitor acivicin [55] in the absence or the presence of the compounds indicated in the figures and the table

4 Antioxidants also act as scavengers by preventing cell and tissue damage

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