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Moreover, the LN microenvironment accelerates epigenetic (60) and metabolic reprogramming of cancer cells (61, 62) that promote resistance to ferroptosis, enhancing survival and metastasis through the blood (62)

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iNOS, inducible nitric oxide synthase, CRP, C-reactive protein

After 30 min, the UVvis absorption spectra at 650 nm was recorded using a Microplate Reader (Victor Nivo , PerkinElmer, USA)

Finally, PPIs inhibit lysosomal acidification by suppressing the neutrophil vacuolar-type H + ATPase (V-ATPase), which ultimately reduces neutrophil antibacterial activity (Song et al., 2017)

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