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The increased demands of Gln in hypercatabolic stress cause high secretion of Gln from skeletal muscle leading to muscle mass loss, a prevalent feature of ICU patients [13]

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Although fructose does not have purine ring and is metabolized through different metabolic pathways compared with purine nucleotides, fructose metabolism depletes intracellular ATP content and markedly increases availability of AMP, which is transformed into UA

Li H, Zhang Z, Zhang H, Guo Y, Yao Z (2021) Update on the pathogenesis and therapy of atopic dermatitis

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