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We treated Ms4a15 OE cells for 48 h with 20:5n-3 (EPA), 22:5n-3 (DPA) and 22:6n-3 (DHA) and observed that longer, more unsaturated DPA and DHA potentiated ferroptosis more robustly than EPA (Fig

Inclusion criteria consisted of newly diagnosed, pathologically confirmed epithelial ovarian cancer, an age of 18 years or older, the ability to provide informed consent, willingness to provide access to medical records, undergoing interval or primary debulking surgery at UPMC/HCC, completing a full course (six cycles) of platinum-based chemotherapy at UPMC/HCC and willingness to provide biospecimens for banking purposes

Detoxification Boost : The sulfur-containing compounds in cruciferous vegetables support liver function and help detox the body by promoting the synthesis of glutathione

The sections were stained with hematoxylin and eosin and images were taken with a Nikon ECLIPSE Ni Upright Microscope (Nikon, Melville, NY) and ONL thickness at six locations relative to the optic nerve were measured: 25% (S3), 50% (S2), and 75% (S1) of the distance between the superior pole and the optic nerve and 25% (I3), 50% (I2), and 75% (I1) of the distance between the inferior pole and the optic nerve

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However, the BHMT reaction is limited to the human liver and kidney since BHMT is expressed primarily in the hepatocytes and kidney cortex (Sunden et al., 1997)