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The dual oxidase Ce-Duox1/BLI-3, a member of the NADPH-oxidase family, is responsible for ROS generation in C

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Hyperfractionated Accelerated Reirradiation for Rectal Cancer: A Large Single-Institution Retrospective Analysis

Utilizing a rat I/R model established by clamping the left hilum of lung for 90 min followed by 120 min of reperfusion, we examined the effects of DEX on lung injury scores, GSH content, and the expression of key proteins involved in cuproptosis

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Factors that might warrant dose adjustment include body weight (with some research using weight-based dosing of 0.5-1.0 mcg/kg), response to first doses (with increases if effects are suboptimal or decreases if adverse effects occur), research phase (with possible dose increases in later phases of long-term protocols), and mix with other research compounds (which may need dose adjustments to account for combined effects)