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Atrial fibrillation is associated with decreased total cerebral blood flow and brain perfusion

Given the clinical relevance of neurons in NPC disease, we performed experiments in the human neuroblastoma SH-SY5Y cell line, which displays many biochemical and functional properties of human neurons and has been widely used as a model for neurodegenerative diseases

Bacopa monnieri alleviates paraquat induced toxicity in Drosophila by inhibiting jnk mediated apoptosis through improved mitochondrial function and redox stabilization

MOTS-c disc research: The direct evidence of MOTS-c preserving disc height and reducing degeneration in animal models positions it as one of the most promising candidates for future clinical development specifically targeting disc disease

This study establishes a causal relationship between phase separation dynamics and inflammasome signalling, proposing the targeted modulation of the phase separation interface as a potential therapeutic paradigm for the treatment of NLRP3-driven pathologies such as sepsis