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Aside from reduced splanchnic perfusion leading to mucosal ischemia and enterocyte damage, factors contributing to the exercise-induced gastrointestinal syndrome might be thermal stress, oxidative stress, effects of gut microbiota, and inflammation [63,64,65]

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Gastrodin enhances remyelination in EAE mice Experimental autoimmune encephalomyelitis (EAE) is a commonly used experimental model for MS [48]

Moreover, stasis of the submucosal blood vessels was present, but the dilatation of veins appeared to be less pronounced (Figure 23B)