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19 BianS.JiangY

Metabolic control of autoimmunity and tissue inflammation in rheumatoid arthritis

Garrett Kriete, sophomore, Deans List, College of Agricultural Sciences and Natural Resources, plant and landscape systems

Cell fractionation Cells were resuspended in fractionation buffer (250 mM sucrose, 20 mM Hepes, 10 mM KCl, 1.5 mM MgCl 2 , 1 mM EGTA, 1 mM EDTA, 1X protease inhibitor cocktail) and then sonicated (4 15 s, 50% amplitude)

Gong, Zhicheng

Therefore, they concluded that RyR2 channel inhibition, but not sodium channel blockade, is likely the principal mechanism of the antiarrhythmic action of flecainide in CPVT