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(Heffernan et al., Endocrinology, 2001) Early human trials: promising but modest Six Phase I/II human clinical trials were conducted, enrolling roughly 900 participants total

Unfortunately, many people struggle to get enough of these nutrients through diet and supplements alone

however, no maternal or fetal complications have been associated with doses that are recommended during pregnancy, and appropriate treatment should not be withheld from pregnant women with vitamin B12 responsive anemias

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Preclinical studies show promise for metabolic health and cellular function

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